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1.
PLoS One ; 17(1): e0262192, 2022.
Article in English | MEDLINE | ID: covidwho-1603690

ABSTRACT

Equal Access to the COVID-19 vaccine for all remains a major public health issue. The current study compared the prevalence of vaccination reluctance in general and COVID-19 vaccine hesitancy and social and health factors associated with intentions to receive the vaccine. A random socio-epidemiological population-based survey was conducted in France in November 2020, in which 85,855 adults participants were included in this study. We used logistic regressions to study being "not at all in favor" to vaccination in general, and being "certainly not" willing to get vaccinated against Covid-19. Our analysis highlighted a gendered reluctance toward vaccination in general but even more so regarding vaccination against COVID-19 (OR = 1.88 (95% CI: 1.79-1.97)). We also found that people at the bottom of the social hierarchy, in terms of level of education, financial resources, were more likely to refuse the COVID-19 vaccine (from OR = 1.22 (95% CI:1.10-1.35) for respondents without diploma to OR = 0.52 (95% CI:0.47-0.57) for High school +5 or more years level). People from the French overseas departments, immigrants and descendants of immigrants, were all more reluctant to the Covid-19 vaccine (first-generation Africa/Asia immigrants OR = 1.16 (95% CI:1.04-1.30)) versus OR = 2.19 (95% CI:1.96-2.43) for the majority population). Finally, our analysis showed that those who reported not trusting the government were more likely to be Covid-19 vaccine-reluctant (OR = 3.29 (95% CI: 3.13-3.45)). Specific campaigns should be thought beforehand to reach women and people at the bottom of the social hierarchy to avoid furthering social inequalities in terms of morbidity and mortality.


Subject(s)
COVID-19/prevention & control , Vaccination Hesitancy/trends , Vaccination Refusal/trends , Adolescent , Adult , Aged , Aged, 80 and over , COVID-19/epidemiology , COVID-19 Vaccines , Cross-Sectional Studies , Female , France/epidemiology , Hostility , Humans , Intention , Male , Middle Aged , SARS-CoV-2/pathogenicity , Socioeconomic Factors , Vaccination/statistics & numerical data , Vaccination Hesitancy/psychology , Vaccination Hesitancy/statistics & numerical data , Vaccination Refusal/psychology , Vaccination Refusal/statistics & numerical data , Vaccines
3.
Sci Rep ; 11(1): 21844, 2021 11 04.
Article in English | MEDLINE | ID: covidwho-1503889

ABSTRACT

This study assesses attitudes towards COVID-19 vaccination and the predictive value of COVID-VAC, a novel scale, among adults in the four largest US metropolitan areas and nationally. A 36-item survey of 6037 Americans was conducted in mid-April 2021. The study reports factors for COVID-19 vaccine acceptance among: (1) already vaccinated; (2) unvaccinated but willing to accept a vaccine; and (3) unvaccinated and unwilling to vaccinate. More than 20% were unwilling to vaccinate, expressing concerns about vaccine efficacy and safety and questioning the disease's severity. Poverty, working outside of the home and conservative political views are predictors of unwillingness. Conversely, those who either personally tested positive for COVID-19, or had a family member who did so, were more likely to accept vaccination. Majorities of all respondents supported vaccination mandates for employees and university students. Respondents preferred to receive vaccines in their doctor´s office. Lower income and conservative ideology, but not race, were strongly associated with vaccine unwillingness. The predictive value of COVID-VAC was demonstrated. While vaccination mandates are likely to be accepted, additional effective, targeted interventions to increase vaccine uptake are needed urgently.


Subject(s)
COVID-19/psychology , Vaccination Refusal/psychology , Vaccination Refusal/trends , Adult , Attitude , COVID-19 Vaccines/administration & dosage , COVID-19 Vaccines/supply & distribution , Female , Guideline Adherence/trends , Health Policy/trends , Humans , Intention , Male , Middle Aged , SARS-CoV-2/pathogenicity , Surveys and Questionnaires , United States , Vaccination/psychology , Vaccination/trends , Vaccines/pharmacology
4.
PLoS One ; 16(10): e0259059, 2021.
Article in English | MEDLINE | ID: covidwho-1496525

ABSTRACT

As safe and effective vaccines become widely available, attaining herd immunity and limiting the spread of COVID-19 will depend on individuals choosing to vaccinate-and doing so quickly enough to outpace mutations. Using online surveys conducted across six Latin American countries in January 2021, we experimentally assess messages designed to counteract informational deficiencies and collective action problems that may drive hesitancy. We first find that basic vaccine information persuades around 8% of hesitant individuals to become willing to vaccinate, reduces intended wait to vaccinate by 0.4 months, and increases willingness to encourage others to vaccinate. Rather than facilitating free riding, learning, or social conformity, additional information about others' behavior increases vaccine acceptance when respondents expect herd immunity will be achieved. Finally, priming the social approval benefits of vaccinating also increases vaccine acceptance. These results suggest that providing information and shaping social expectations and incentives could both significantly increase vaccine uptake.


Subject(s)
COVID-19/psychology , Vaccination Refusal/psychology , Vaccination/psychology , COVID-19/prevention & control , COVID-19 Vaccines/therapeutic use , Health Knowledge, Attitudes, Practice , Humans , Latin America , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , Persuasive Communication , SARS-CoV-2/pathogenicity , Surveys and Questionnaires , Vaccination/statistics & numerical data , Vaccination Refusal/trends , Vaccines/pharmacology
6.
Brain Res Bull ; 176: 161-173, 2021 11.
Article in English | MEDLINE | ID: covidwho-1413366

ABSTRACT

The COVID-19 pandemic has persisted for more than a year, and post-COVID-19 sequelae of neurological complications, including direct and indirect effects on the central nervous system (CNS), have been recognized. There is a plethora of evidence for neurological, cognitive, and emotional deficits in COVID-19 patients. Acute neurological symptoms like neuroinflammation, cognitive impairment, loss of smell, and brain stroke are common direct effects among SARS-CoV-2 infected individuals. Work-associated stress, lockdowns, social distancing, and quarantine in response to contain SARS-CoV-2 have also affected the mental health of large populations, regardless of age. Public health emergencies have affected individuals and communities, resulting in emotional reactions and unhealthy behaviors. Although vaccines have been widely distributed and administered among large populations, vaccine hesitancy still exists and may be due to apprehension about vaccine efficacy, preliminary trials, and associated side effects. This review highlights the impact of COVID-19 on the CNS by outlining direct and indirect effects and factors contributing to the decline in people's mental health throughout the COVID-19 pandemic both during and after vaccine administration. Furthermore, we also discuss reasons for vaccine hesitancy and why some groups of people are deprived of vaccines. Finally, we touched upon the social determinants of mental health and their impact on disadvantaged populations during times of crisis which may help policymakers set up some action plans to mitigate the COVID-19 mental health turmoil during this ongoing pandemic.


Subject(s)
COVID-19/psychology , Vaccination Refusal/psychology , Vaccination/psychology , COVID-19 Vaccines/administration & dosage , Communicable Disease Control , Humans , Longitudinal Studies , Mental Health/trends , Pandemics/prevention & control , Public Health , SARS-CoV-2/pathogenicity , Vaccination/trends , Vaccination Refusal/trends , Vaccines
7.
Expert Rev Vaccines ; 20(8): 921-933, 2021 08.
Article in English | MEDLINE | ID: covidwho-1305400

ABSTRACT

Introduction: Acceptance of COVID-19 vaccines is critical to personal health, protecting vulnerable populations, reopening socio-economic life, and achieving population health and safety through immunity. The primary aim of this review was to investigate the extent and determinants of COVID-19 vaccine hesitancy in South Africa to inform the development of strategies to address it. A secondary aim was to enhance understandings of and responses to vaccine hesitancy more generally in South Africa, with potential positive effect on vaccination uptake during and beyond the COVID-19 pandemic.Areas covered: We reviewed the findings from surveys conducted in South Africa from February 2020 to March 2021 that investigated acceptance of COVID-19 vaccines. Surveys were identified through searching electronic databases of peer-reviewed and gray literature and contacting experts.Expert opinion: The review reveals the inherently social nature of COVID-19 vaccine hesitancy in South Africa, potentially influenced by age, race, education, politics, geographical location, and employment. Along with the provision of information, COVID-19 vaccine communication strategies need to form part of broader trust-building measures that focus on relationships, transparency, participation, and justice. The pandemic also provides a unique opportunity to positively intervene and reduce vaccine hesitancy trends more generally in South Africa and potentially elsewhere.


Subject(s)
COVID-19 Vaccines/administration & dosage , COVID-19/psychology , Vaccination Refusal/psychology , COVID-19/epidemiology , COVID-19/prevention & control , Humans , Patient Acceptance of Health Care/psychology , South Africa/epidemiology , Vaccination/psychology , Vaccination/trends , Vaccination Refusal/trends
11.
PLoS Biol ; 19(3): e3001167, 2021 03.
Article in English | MEDLINE | ID: covidwho-1121937

ABSTRACT

As the vaccines against COVID are slowly becoming available, we need to consider the paradox of why so many people of color are dying from the disease yet cannot get the vaccinations. Concerns focus on vaccine refusal but lack of access is the bigger problem.


Subject(s)
Black or African American/psychology , COVID-19/ethnology , Hispanic or Latino/psychology , Racism/psychology , Vaccination Refusal/ethnology , COVID-19/epidemiology , COVID-19/psychology , COVID-19 Vaccines/metabolism , COVID-19 Vaccines/pharmacology , Humans , Pandemics , SARS-CoV-2/isolation & purification , United States/epidemiology , Vaccination/methods , Vaccination/psychology , Vaccination Refusal/psychology , Vaccination Refusal/trends
12.
Vaccine ; 39(14): 1877-1881, 2021 04 01.
Article in English | MEDLINE | ID: covidwho-1118714

ABSTRACT

The COVID-19 pandemic has produced many calls for a vaccine. There is growing concern that vaccine hesitancy and anti-vaccination presence will dampen the uptake of a coronavirus vaccine. There are many cited reasons for vaccine hesitancy. Mercury content, autism association, and vaccine danger have been commonly found in anti-vaccination messages. It is also mused that the reduced disease burden from infectious diseases has paradoxically reduced the perceived requirement for vaccine uptake. Our analysis using Google Trends has shown that throughout the pandemic the search interest in a coronavirus vaccine has increased and remained high throughout. Peaks are found when public declarations are made, the case number increases significantly, or when vaccine breakthroughs are announced. Anti-vaccine searches, in the context of COVID-19, have had a continued and growing presence during the pandemic. Contrary to what some may believe, the burden of coronavirus has not been enough to dissuade anti-vaccine searches entirely.


Subject(s)
COVID-19 Vaccines/administration & dosage , COVID-19/prevention & control , Vaccination Refusal/trends , Anti-Vaccination Movement , Humans , Pandemics , Vaccination
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